Dihexa – 100mg Vial (Lyophilized Peptide Powder) – Research Use Only

Alias: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Category: HGF-Mimetic Cognitive Enhancer
Molecular Formula: C₂₇H₄₈N₆O₄
Molecular Weight: ~520.72 g/mol
Purity: ≥98% (HPLC Verified)
Research Use Only – Not for Human or Veterinary Use

Overview:

Dihexa is a lipophilic oligopeptide compound derived from angiotensin IV analogues and developed as a potent hepatocyte growth factor (HGF)/c-Met pathway activator. Its primary research interest lies in neuroregeneration and synaptogenesis, with preclinical studies suggesting Dihexa may outperform brain-derived neurotrophic factor (BDNF) in promoting synaptic connectivity and cognitive function in damaged or aging neural networks.

Originally synthesized at Washington State University, Dihexa represents a new class of blood-brain barrier permeable, neurotrophic peptide mimetics. It is currently used in advanced neuroscience research to evaluate memory formation, Alzheimer’s models, stroke recovery, and traumatic brain injury repair.

Key Research Focus Areas:

• Cognitive Enhancement Models: Dihexa has shown significant improvement in learning, memory retention, and pattern recognition in animal models.

• Neuroplasticity & Synaptogenesis: Activates HGF/c-Met signaling, stimulating new synapse formation and neuronal connectivity.

• Neurodegenerative Disease Research: Investigated in models of Alzheimer’s, Parkinson’s, frontotemporal dementia, and age-related decline.

• Trauma & Stroke Recovery: Explored for its role in rebuilding damaged neural networks, particularly post-ischemic insult.

• BDNF Alternative: Unlike BDNF, which has poor bioavailability and transport issues, Dihexa is highly bioavailable and BBB-permeable in rodent studies.

Presentation:

• Supplied as 100mg of Dihexa in sterile, lyophilized powder per vial.

• For in vitro research applications only. Reconstitution recommended with bacteriostatic water or suitable solvent depending on assay design.

Storage Guidelines:

• Store lyophilized vial at 2°C to 8°C, shielded from moisture and UV light.

• Reconstituted solution should be kept at 2°C to 4°C and used within 10–14 days.

• Avoid multiple freeze-thaw cycles.

⚠️ Disclaimer:

This product is strictly intended for scientific and laboratory research use only. It is not approved for human ingestion, therapeutic use, or veterinary administration. Information provided is based solely on preclinical and in vitro research data and is not intended as medical advice. Only licensed laboratories and qualified personnel may handle this compound in accordance with applicable laws.