Deslorelin 100mg Vial (Lyophilized Peptide Powder) – Research Use Only

Alias: [D-Trp6]-GnRH; Deslorelin Acetate
Molecular Formula: C₅₆H₇₆N₁₆O₁₂
Sequence: Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt
Molecular Weight: ~1282.5 g/mol
Purity: ≥98% (HPLC Verified)
Research Use Only – Not for Human or Veterinary Use

Overview:

Deslorelin is a synthetic gonadotropin-releasing hormone (GnRH) superagonist designed to mimic and enhance the action of endogenous GnRH while inducing downregulation of pituitary gonadotropin receptors over time. Though it has been employed clinically in veterinary endocrinology and human reproductive medicine, this version is designated strictly for laboratory and in vitro research use.

It has become a prominent subject of research for its dual-phase action—initially stimulating the release of LH and FSH, followed by receptor desensitization leading to suppression of sex hormone production (testosterone, estrogen). These mechanisms make Deslorelin particularly relevant in studies on fertility control, hormone-sensitive cancers, and androgen deprivation models.

Key Research Focus Areas:

• Androgen Suppression Models: Used in studies on prostate cancer, precocious puberty, and chemical castration through testosterone downregulation.
• Ovulation Control & Fertility Suppression: Frequently studied in veterinary reproductive control (e.g. dogs, ferrets, horses) and has translational interest in temporary female contraceptive research.
• Endocrine Axis Research: Ideal for experiments analyzing hypothalamic-pituitary-gonadal (HPG) feedback loops and GnRH receptor regulation.
• Hormone Pulsatility Modeling: Investigated for its unique ability to cause biphasic effects depending on dose, frequency, and receptor status—initial stimulation followed by functional suppression.

Presentation:

• Supplied in sterile lyophilized form. Available in either 100mcg or 1000mcg (1mg) concentrations per vial.
• Requires dilution with bacteriostatic water or suitable laboratory solvent before in vitro use.

Storage Guidelines:

• Store lyophilized powder between 2°C and 8°C (refrigerated).
• After reconstitution, maintain at 2°C to 4°C and use within 10–14 days.
• Avoid repeated freeze-thaw cycles and exposure to direct light.

⚠️ Disclaimer:

This compound is sold for research and laboratory use only. It is not intended for human or veterinary administration, drug development, diagnostic procedures, or therapeutic use. All information provided is for scientific and educational purposes only. Use is restricted to qualified professionals in licensed research settings.